Combinatorial chemistry: starting the second decade

Neoplasia: the second decade.

This issue marks the end of the 10-year anniversary of Neoplasia where we have seen exciting growth in both number of submitted and published articles in Neoplasia. Neoplasia was first published in 1999. During the past 10 years, Neoplasia has dynamically adapted to the needs of the cancer research community as technologies have advanced. Neoplasia is currently providing access to articles thro...

ARticipating the Second Decade

The research efforts described in this book may paradoxically appear to be both hideously complex and yet ridiculously simplistic-complex in the range of concepts they attempt to capture, encode, and use effective!.'}, but simplistic in the important areas of human knowledge and common sense that they ignore (but that we know can be crucial to excellent clinical decision making). Viewed in this...

the second immanant of some combinatorial matrices

let $a = (a_{i,j})_{1 leq i,j leq n}$ be an $n times n$ matrixwhere $n geq 2$. let $dt(a)$, its second immanant be the immanant corresponding to the partition $lambda_2 = 2,1^{n-2}$. let $g$ be a connected graph with blocks $b_1, b_2, ldots b_p$ and with$q$-exponential distance matrix $ed_g$. we given an explicitformula for $dt(ed_g)$ which shows that $dt(ed_g)$ is independent of the manner in ...

Combinatorial chemistry

Combinatorial chemistry, which did not even exist fifteen years ago, is a new subfield of chemistry that is starting to provide insights into molecular interactions, biochemical catalysis and drug development. Instead of finding and testing naturally existing compounds for useful activity, the basic aim of combinatorial chemistry studies is to create vast numbers of new, synthetic compounds and...

Combinatorial chemistry.